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Product Infomation
Product Name TiO₂ Magnetic Beads, 5 μm (Thin Shell)
Catalog Number MGB-EI-003
Size 2 mL, 5 mL, 10 mL
Physical Specs 5 μm
meta keywords TiO₂ Magnetic; 5 μm; Thin Shell; Exosome Isolation; Phosphorylated Protein; Cell Vesicle
meta description Matexcel provides TiO₂ Magnetic Beads, 5 μm (Thin Shell) for efficient separation of exosomes and phosphorylation analysis in proteomics.
Cat NO MGB-EI-003
Description Titanium dioxide exhibits selective affinity for phosphoserine (pSer), phosphothreonine (pThr), and phosphotyrosine (pTyr) residues. TiO₂ magnetic beads are proprietary magnetic particle carriers that enable simple, convenient, efficient, highly specific, and reproducible enrichment of phosphopeptides from protein digests in complex biological samples. The TiO₂ nanoparticles on the bead surface show no significant preference for mono- or multi-phosphorylated peptides, making them ideal for one-step phosphopeptide enrichment in mass spectrometry-based proteomics. In addition, TiO₂ magnetic beads can isolate extracellular vesicles (EVs) such as exosomes by binding phospholipid bilayers. TiO₂ captures small EVs (sEVs) by forming bidentate structures with phosphate groups in the EV phospholipid bilayer, and the magnetic core allows further separation of bead-sEV complexes. Binding is reversible; captured sEVs can be eluted and collected by washing with alkaline solution.
Applications Used for the separation of extracellular vesicles (EVs) such as exosomes
Features High specificity for phosphorylated peptides and exosomes; no significant preference for monophosphorylated or polyphosphorylated peptides; rapid magnetic response time of less than 30 seconds, reducing sample loss and making it more suitable for automated operations; antioxidant properties reduce the risk of sample contamination.
Particle Size 5 μm
Concentration 25 mg/mL
Surface Groups TiO2
Storage Solution Ultrapure water
Storage 2-8°C
Shelf Life 3 years
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