Nanodiamond Service

Nanodiamond (ND) is a diamond-like carbon nanoparticle that has gained significant attention due to its distinct optical, thermal, and mechanical properties compared to other carbon nanomaterials (e.g., graphene, carbon nanotubes, carbon dots). Combined with a high surface-to-volume ratio and tunable, chemically versatile surfaces, these characteristics support broad applications across catalysis, electronics, and life sciences. Moreover, the biocompatible nature of NDs enables their controllable interfacial interactions with biological systems, positioning them as excellent candidates for advancing cutting-edge biomedical sciences.

Matexcel provides one-stop technical services from nanodiamond synthesis and production to comprehensive characterization and analysis, supporting innovative research for academic institutions and enterprises in catalysis, electronics, life sciences, and other fields.

Nanodiamond crystals. Photo courtesy from John C. Angus, "Diamond Lab," Case Western Reserve University, 1998.

Core Service Portfolio

1. Nanodiamond Production & Custom Synthesis

• Detonation Synthesis: Scalable production of high-purity nanodiamonds (1-100 nm)
• Surface Functionalization: Chemical modifications including carboxylation, amination, and hydroxylation
• Fluorescent Labeling: Preparation of fluorescent nanodiamonds (FNDs) with nitrogen-vacancy (NV) centers
• Particle Size Control: Precise tuning of size distributions (5 nm, 30 nm, 70 nm, 100 nm, etc.)
• Dispersion System Optimization: Preparation of aqueous and organic solvent dispersions

2. Analysis & Characterization Services

• Basic Physical Property Characterization:
  • TEM/SEM morphology and particle size analysis
  • XRD crystal structure identification
  • Raman Spectroscopy
  • Dynamic Light Scattering (DLS) for size distribution
  • Zeta potential measurement
• Surface Chemical Analysis:
  • FTIR spectroscopy
  • X-ray Photoelectron Spectroscopy (XPS)
  • Thermogravimetric Analysis (TGA)
  • Elemental analysis (CHN/O)
• Biomedical-Specific Analysis:
  • Cytotoxicity testing (MTT/CCK-8)
  • Fluorescence performance testing (fluorescence spectra, quantum yield)
  • Drug loading and release kinetics
  • Protein adsorption performance evaluation
  • Hemocompatibility testing

Core Advantages of Nanodiamonds

Excellent Biocompatibility

• Low cytotoxicity, suitable for in vitro and in vivo biomedical research
• Good hemocompatibility, reducing immune rejection

Unique Physicochemical Properties

• Ultra-high mechanical strength and chemical stability
• High thermal conductivity and optical transparency
• Tunable surface chemistry

High Specific Surface Area & Loading Capacity

• Surface area of approximately 300-500 m²/g
• Efficient loading of drugs, proteins, and nucleic acids (loading efficiency up to 80-90%)

Controlled Release & Long-Term Stability

• pH/temperature/enzyme-responsive release systems
• Protects drugs from degradation and extends circulation time

Multimodal Imaging & Theranostics Integration

• Fluorescent nanodiamonds for real-time bioimaging (NV centers provide stable fluorescence)
• Combined diagnostic and therapeutic functions (theranostics)

Scalable Production & Economic Feasibility

• Detonation method is cost-effective, supporting kilogram-scale production
• Stable quality with good batch-to-batch reproducibility

Primary Application Areas

Standard Service Workflow

Our Technical Advantages

Advanced Synthesis Platform

• Detonation synthesis reactor with kilogram-scale annual production capacity
• Particle size distribution control accuracy of ±5%
• Batch-to-batch consistency CV < 10%

Comprehensive Characterization System

• 20+ sets of advanced analytical equipment
• ISO 17025 compliant quality management system
• Active participant in multiple industry standard development initiatives

Expert Technical Team

• Interdisciplinary specialists in materials science, chemistry, and biomedical engineering
• Over 10 years of experience in nanomaterials R&D
• 50+ published SCI papers in relevant fields

Customized Service Capability

• Flexible customization from mg to kg scale
• Rapid response for urgent orders (delivery in as fast as 3 business days)
• Full-process support from lab to pilot-scale production

Sample Requirements & Submission Guidelines

Information You Need to Provide:

Customer Sample Submission Requirements (if analysis services needed):

• Sample State: Powder or dispersion; minimum 100mg (solid) or 5mL (liquid, concentration ≥1mg/mL) recommended
• Packaging: Leak-proof sealed container with clear sample ID labeling
• Safety Information: Provide MSDS or chemical safety information
• Shipping Conditions: Ambient temperature or 4°C with ice packs (avoid extreme temperatures)

Online Inquiry

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