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Product Infomation
Product Name SUV HSPC-CHOL-mPEG2000-DSPE LNP with (NH₄)₂SO₄ Gradient (85 nm)
Catalog Number R-ZZTBSSDL-126
Alias Small unilamellar liposomes with ammonium sulfate gradient (hydrogenated soy phosphatidylcholine-cholesterol-methoxypolyethylene glycol 2000-DSPE, molar ratio 56.2:38.5:5.3, particle size 85 nm)
Appearance Translucent to slightly opalescent homogeneous dispersion
Molecular Formula N/A
Solubility Can be reconstituted/diluted in isotonic buffer
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Research on active drug loading mechanism and release kinetics
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description SUV HSPC-CHOL-mPEG2000-DSPE Liposomes with (NH₄)₂SO₄ Gradient (85 nm) is an advanced liposome platform that combines long circulation properties and active drug loading capabilities. It is a small unilamellar vesicle structure. It uses an optimized HSPC:CHOL:DSPE-mPEG2000 (56.2:38.5:5.3 mol:mol) formula, accurately controls the particle size at ~85 nm through extrusion technology, and establishes a stable ammonium sulfate transmembrane gradient. In this formula, high phase transition temperature HSPC and a high proportion of cholesterol build an extremely dense and stable gel film, while 5.3 mol% DSPE-mPEG2000 forms a hydrated polymer layer on its surface, giving it "stealth" properties to extend the circulation time in the body.
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