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Product Infomation
Product Name SIS3 HCl@Liposome NPs​, SIS3 hydrochloride@liposome nanoparticles​
Catalog Number R-CW-LPS0 03
Alias SIS3 hydrochloride@Liposome nanoparticles
Appearance Dispersion​
Molecular Formula N/A
Solubility Dispersed in aqueous medium​
Storage -20°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Research on cell signal transduction mechanism​
Specification 10mg：Inquiry
20mg：Inquiry
50mg：Inquiry
Description SIS3 hydrochloride@liposomal nanoparticles are a drug delivery system. Liposomes serve as carriers and are made of natural or synthetic phospholipids and other lipid materials that spontaneously form a bilayer structure in aqueous solution, effectively encapsulating the biologically active SIS3 hydrochloride in it. SIS3 hydrochloride is a small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3). It can specifically block the STAT3 signaling pathway and interfere with the proliferation, survival, and metastasis of tumor cells. The average particle size of liposome nanoparticles ranges from tens to hundreds of nanometers, and this nanoscale size gives the product some advantages. On the one hand, its particle size is similar to the pore size of biological membranes, which is conducive to entering cells through endocytosis, thereby achieving accurate regulation of intracellular STAT3 signaling pathways; on the other hand, the large specific surface area of ​​nanoparticles increases the contact area between liposomes and cells, improving the efficiency and targeting of drug delivery. In in vitro experiments, SIS3 hydrochloride@liposome nanoparticles can effectively inhibit the growth of tumor cells and induce tumor cell Apoptosis. Compared with free SIS3 hydrochloride, the liposome-encapsulated product exhibits better stability and cellular uptake rate, reducing drug distribution in non-target tissues and reducing potential side effects.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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