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Product Infomation
Product Name Single Chamber Membrane-based Microfluidic Chip
Catalog Number OOC-006
Description The single-chamber membrane chip features independent upper and lower flow channels separated by a biocompatible porous membrane. Different cell types can be cultured on either side of the membrane, interacting through the porous membrane to construct a tissue barrier interface structure similar to that found in the human body. Additionally, by integrating fluid flow and immune cells, the chip can reproduce the complex biological microenvironment found in vivo.
Applications Construction of individual barrier organoid models, such as liver, intestinal, lung, skin, kidney, and blood-brain barrier models; development of disease models, such as IPF and DM models; drug screening and toxicity assessment; evaluation of cosmetic safety and efficacy; and basic scientific research, such as mechanisms of inflammation, drug resistance, and viral infection.
Features Enables the stable construction of classic multi-layer and barrier-function organ-on-a-chip models. Can function as an independent unit to facilitate serial interactions among multi-level barrier organoid units. Independent control of upper and lower chambers enables continuous unidirectional perfusion culture via gas-liquid or liquid-liquid methods; when paired with a fluid control system, flow rates can be precisely regulated. A single chip can accommodate two series-connected tissue-organ units (dual-chamber membrane chips) to study interactions between two tissues or organs. The addition of a bubble collection unit eliminates cell damage caused by bubbles during culture. The upper and lower chambers are separated by a porous membrane, ensuring the independence of cells and tissues while simulating the hierarchical structure of cells at tissue interfaces within human organs. This setup facilitates the exchange of substances and signals.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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