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Product Infomation
Product Name Rosiglitazone@LNP-CGKRK, rosiglitazone-lipid nanoparticle-CGKRK targeting peptide complex
Catalog Number R-LNP-02
Alias Rosiglitazone@LNP-peptide
Appearance Milky white or transparent colloidal solution
Molecular Formula N/A
Solubility Soluble in organic solvents
Storage -20°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Targeted antitumor therapy
Specification 10mg：Inquiry
25mg：Inquiry
50mg：Inquiry
Description Rosiglitazone@LNP-CGKRK peptide is an innovative drug delivery complex that combines the Treatment advantages of rosiglitazone with the delivery capabilities of LNP and the targeting properties of CGKRK peptide. Rosiglitazone, a thiazolidinedione drug, can increase insulin sensitivity by activating peroxisome proliferator-activated receptor γ (PPARγ) and effectively assist in controlling blood sugar levels in patients with type 2 diabetes. Lipid nanoparticles (LNP) are composed of ionizable cationic lipids, phospholipids, cholesterol and PEGylated lipids, which can stably encapsulate rosiglitazone, protect it from degradation, prolong the circulation time of the drug in the body, and enhance drug stability. The CGKRK peptide is a cell-penetrating peptide with an amino acid sequence that can carry substances connected to it across the cell membrane, helping rosiglitazone to enter target cells more efficiently, improving drug delivery efficiency, enhancing the effect on target cells, and is expected to play a greater role in the field of diabetes treatment.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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