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| Product Name | Rocaglamide LNP, Rocaglamide liposome formulation |
| Catalog Number | R-ZZTBSSDL-103 |
| Alias | ROC-A nanoliposomes (KHE9A prescription) |
| Appearance | Milky white to light yellow homogeneous suspension |
| Molecular Formula | N/A |
| Solubility | Can be reconstituted in physiological buffer (such as PBS) or 5% glucose solution to form a stable colloidal dispersion system |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 year |
| Shipping Condition | low temperature transport |
| Application | Development of nanodelivery system for eIF4A targeted inhibitors |
| Specification | 10mg:Inquiry 20mg:Inquiry 50mg:Inquiry |
| Description | Rocaglamide LNP is a special nanoliposome preparation of the natural anti-tumor compound Rocaglamide (ROC-A), which is encapsulated using the systematically screened and optimized formula KHE9A. As a potent eIF4A translation initiation inhibitor, ROC-A can selectively inhibit protein synthesis in a variety of tumor cells. However, its low water solubility, unstable chemical properties, and non-in vivo distribution limit its clinical application. |