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Product Infomation
Product Name Rocaglamide LNP, Rocaglamide liposome formulation
Catalog Number R-ZZTBSSDL-103
Alias ROC-A nanoliposomes (KHE9A prescription)
Appearance Milky white to light yellow homogeneous suspension
Molecular Formula N/A
Solubility Can be reconstituted in physiological buffer (such as PBS) or 5% glucose solution to form a stable colloidal dispersion system
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Development of nanodelivery system for eIF4A targeted inhibitors
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description Rocaglamide LNP is a special nanoliposome preparation of the natural anti-tumor compound Rocaglamide (ROC-A), which is encapsulated using the systematically screened and optimized formula KHE9A. As a potent eIF4A translation initiation inhibitor, ROC-A can selectively inhibit protein synthesis in a variety of tumor cells. However, its low water solubility, unstable chemical properties, and non-in vivo distribution limit its clinical application.
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