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Product Infomation
Product Name Recombinant Mouse Vascular Endothelial Growth Factor, 121 a.a.
Catalog Number VGF-004
Size 2µg;10µg;1mg
Description Vascular Endothelial Growth Factor (VEGF) is an important signaling protein involved in angiogenesis and vasculogenesis. As the name suggests, VEGF’s activity has primarily been studied in vascular endothelial cells, but it also affects other cell types (such as stimulating the migration of monocytes/macrophages, neurons, cancer cells, and renal epithelial cells). VEGF mediates increased vascular permeability, induces angiogenesis, vascular formation, and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro experiments have shown that VEGF stimulates endothelial cell mitosis and cell migration. VEGF is also a vasodilator that increases microvascular permeability; it was originally referred to as a vascular permeability factor.
Application This product can be used for research on facilitating murine angiogenesis studies with mouse VEGF 121 a.a. isoform.
Molecular Weight 28.4 kDa
Species Mouse
Source E.coli
Appearance Sterile-filtered white lyophilized powder
Purity ≥ 97% by SDS-PAGE, RP-HPLC
Redissolution It is recommended to reconstitute lyophilized VEGF-121 with sterile 18 MΩ-cm H₂O to a concentration of at least 100 µg/mL, after which it may be further diluted into other aqueous solutions.
Formulation This protein was lyophilized from a 1 mg/mL solution and contains no additives.
Amino Acid Sequence MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKCDKRPR R
Storage Store at room temperature for 3 weeks, or in a dry environment at -18°C or below. After reconstitution, store at 4°C for 2-7 days; thereafter, store at -18°C or below for future use. Avoid repeated freeze-thaw cycles.
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