We can offer a discount on bulk orders. Please contact our sales team for further inquiry.
Product Infomation
Product Name Recombinant Human Platelet-Derived Growth Factor Receptor, Beta
Catalog Number PGF-012
Size 2µg;10µg;1mg
Description Platelet-derived growth factor receptor β (PDGFRB) belongs to the receptor tyrosine kinase (RTK) III subfamily, which also includes the receptors for Flt3 ligand, SCF, and M-CSF. PDGFRB plays a critical role in vascular development by promoting the growth, migration, and recruitment of pericytes and smooth muscle cells to endothelial cells. PDGFRB also contributes to actin cytoskeletal reorganization and the formation of membrane invaginations. PDGFRB phosphorylates NCK1, PIK3R1, PTPN11, CBL, SHC1, RASA1/GAP, and PLCG1.
Application This product can be used for research on investigating PDGF receptor beta signaling in tissue engineering with human PDGFR-β.
Molecular Weight 83.3 kDa
Species Human
Source Sf9, Insect cells
Appearance Sterile-filtered colorless solution
Purity ≥ 90% by SDS-PAGE
Formulation The PDGFRB protein solution (0.25 mg/mL) contains phosphate-buffered saline (pH 7.4) and 10% glycerol.
Amino Acid Sequence LVVTPPGPEL VLNVSSTFVL TCSGSAPVVW ERMSQEPPQE MAKAQDGTFS SVLTLTNLTG LDTGEYFCTH NDSRGLETDE RKRLYIFVPD PTVGFLPNDA EELFIFLTEI TEITIPCRVT DPQLVVTLHE KKGDVALPVP YDHQRGFSGI FEDRSYICKT TIGDREVDSD AYYVYRLQVS SINVSVNAVQ TVVRQGENIT LMCIVIGNEV VNFEWTYPRK ESGRLVEPVT DFLLDMPYHI RSILHIPSAE LEDSGTYTCN VTESVNDHQD EKAINITVVE SGYVRLLGEV GTLQFAELHR SRTLQVVFEA YPPPTVLWFK DNRTLGDSSA GEIALSTRNV SETRYVSELT LVRVKVAEAG HYTMRAFHED AEVQLSFQLQ INVPVRVLEL SESHPDSGEQ TVRCRGRGMP QPNIIWSACR DLKRCPRELP PTLLGNSSEE ESQLETNVTY WEEEQEFEVV STLRLQHVDR PLSVRCTLRN AVGQDTQEVI VVPHSLPFKV LEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH
Storage Store at 4°C for 2-4 weeks. For long-term storage, freeze at -20°C. For long-term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
Online Inquiry
For Research or Industrial Raw Materials, Not For Personal Medical Use!
Place the Order
FAQs
logo

Enter your email here to subscribe.

Copyright © MATEXCEL. All Rights Reserved.
0
Inquiry Basket