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Product Infomation
Product Name Recombinant Human Platelet-Derived Growth Factor B
Catalog Number PGF-004
Size 2µg;10µg;1mg
Description The term “PDGF” refers to a class of disulfide-linked dimeric isoforms that function as autocrine and paracrine growth factors and are produced by various cell types other than platelets. They exert potent mitogenic effects on nearly all mesenchymal-derived cells. Abnormal expression is associated with certain cancers, fibroproliferative diseases, and atherosclerosis. The protein also contributes to wound healing and nerve regeneration. The PDGF family comprises four members: PDGF-A, PDGF-B, PDGF-C, and PDGF-D. PDGF-A exists in two distinct forms: a soluble short-chain form and a long-chain form that remains anchored in the extracellular matrix.
Application This product can be used for research on promoting cell migration and proliferation in vascular tissue engineering with human PDGF-B.
Molecular Weight 16.75 kDa
Species Human
Source E.coli
Appearance Sterile-filtered colorless solution
Purity ≥ 95% by SDS-PAGE
Formulation Platelet-derived growth factor-B was prepared in 25 mM sodium acetate, pH 4.8, 1 mM EDTA, and 50% glycerol.
Storage Store at 4°C for 2-4 weeks. For long-term storage, freeze at -20°C. For long-term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
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