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Product Infomation
Product Name Recombinant Human Endocrine Gland Vascular Endothelial Growth Factor
Catalog Number VGF-001
Size 5µg;20µg;1mg
Description Endocrine-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in endocrine-derived capillary endothelial cells. Its expression is hypoxia-induced and restricted to steroid-producing glands (ovaries, testes, adrenal glands, and placenta). Its expression typically complements that of VEGF, suggesting that these molecules act in a coordinated manner. EG-VEGF potently contracts gastrointestinal smooth muscle. It induces proliferation, migration, and fenestration (i.e., the formation of membrane discontinuities) in endocrine-derived capillary endothelial cells. It has little effect on other types of endothelial or non-endothelial cells.
Application This product can be used for research on promoting endocrine gland vascularization in tissue engineering with human EG-VEGF.
Molecular Weight 9.7 kDa
Species Human
Source E.coli
Appearance Sterile-filtered white lyophilized powder
Purity ≥ 95% by SDS-PAGE
Activity Activity is determined by the dose-dependent proliferation of MIA PaCa-2 cells, typically at 1-4 μg/mL.
Redissolution It is recommended to reconstitute the lyophilized endocrine gland vascular endothelial growth factor (VEGF) with sterile 18 MΩ-cm H₂O to a concentration of at least 100 µg/mL, after which it may be further diluted into other aqueous solutions.
Formulation This protein was lyophilized from a concentrated (1 mg/mL) solution containing 0.1% trifluoroacetic acid (TFA).
Amino Acid Sequence AVITGACERD VQCGAGTCCA ISLWLRGLRM CTPLGREGEE CHPGSHKVPF FRKRKHHTCP CLPNLLCSRF PDGRYRCSMD LKNINF
Storage Store at room temperature for 3 weeks, or in a dry environment at -18°C or below. After reconstitution, store at 4°C for 2-7 days; thereafter, store at -18°C or below for future use. Avoid repeated freeze-thaw cycles.
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