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Product Infomation
Product Name Recombinant Human Connective Tissue Growth Factor, His
Catalog Number CGF-002
Size 5µg;20µg;1mg
Description Connective Tissue Growth Factor belongs to the CCN protein family. The CCN family currently comprises six members in humans, also known as: Cyr61 (Cysteine-rich 61), CTGF (Connective Tissue Growth Factor), Nov (Nephroblastoma Overexpression Gene), and WISP-1, 2, and 3 (Wnt-1-induced secreted proteins). CCN genes encode secreted proteins associated with the extracellular matrix (ECM) and cell membranes. CCN proteins are extracellular matrix proteins involved in the regulation of various cellular functions, including proliferation, differentiation, survival, adhesion, and migration. They are expressed in derivatives of the embryonic three germ layers and participate in the development of the kidneys, nervous system, muscles, bone marrow, cartilage, and skeleton. In adulthood, they are involved in wound healing, fracture repair, and pathological processes such as fibrosis, vascular diseases, and tumorigenesis.
Application This product can be used for research on enabling affinity purification and tracking in connective tissue engineering using His-tagged human CTGF.
Molecular Weight 37.7 kDa
Species Human
Source E.coli
Appearance Sterile-filtered colorless solution
Purity ≥ 85% by SDS-PAGE
Formulation CTGF protein (1 mg/mL) was dissolved in 20 mM Tris-HCl (pH 8) and 10% glycerol.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH M QNCSGPCRC PDEPAPRCPA GVSLVLDGCG CCRVCAKQLG ELCTERDPCD PHKGLFCDFG SPANRKIGVC TAKDGAPCIF GGTVYRSGES FQSSCKYQCT CLDGAVGCMP LCSMDVRLPS PDCPFPRRVK LPGKCCEEWV CDEPKDQTVV GPALAAYRLE DTFGPDPTMI RANCLVQTTE WSACSKTCGM GISTRVTNDN ASCRLEKQSR LCMVRPCEAD LEENIKKGKK CIRTPKISKP IKFELSGCTS MKTYRAKFCG VCTDGRCCTP HRTTTLPVEF KCPDGEVMKK NMMFIKTCAC HYNCPGDNDI FESLYYRKMY GDMA
Storage Store at 4°C for 2-4 weeks. For long-term storage, freeze at -20°C. For long-term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
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