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Product Infomation
Product Name Recombinant Human Acidic Fibroblast Growth Factor
Catalog Number FGF-006
Size 100µg;1mg;10mg;100mg
Description Acidic Fibroblast Growth Factor (aFGF), also known as FGF1, belongs to the FGF family and participates in tissue repair. It exerts trophic and mitogenic effects on various cells of mesodermal and neuroectodermal origin, such as BALB/c 3T3 fibroblasts, capillary and endothelial cells, myoblasts, vascular smooth muscle cells, endothelial cells, glial and astrocytes, and adrenal cortical cells, among others, and possesses broad biological effects and potential clinical application value.The aFGF molecule contains a heparin-binding region; upon binding to heparin, aFGF can increase its activity toward certain cells, and a certain amount of heparin can enhance the stability of aFGF, preventing its denaturation by heat or extreme pH conditions and its hydrolysis by proteases.
Application This product can be used for research on inducing angiogenesis and fibroblast proliferation for vascularized tissue constructs with human acidic FGF.
Molecular Weight 16.0 kDa
Species Human
Source E.coli
Appearance Freeze-dried powder; pre-freeze-drying solution: 10 mM PBS (pH 6.0)
Purity ≥ 95% by SDS-PAGE
Endotoxin Level < 50 EU/mg
Activity ≥ 2.5×10⁵ IU/mg protein (dose-dependent proliferation assay using mouse BALB/c 3T3 cells)
Isopotential Point 7.73
Extinction Coefficient Extinction coefficient E (0.1% at 280 nm)=1.091
Storage Store at -20°C.
Shelf Life 3 years
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