Protein L Magnetic Beads, 200 nm

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Product Infomation

Product Name	Protein L Magnetic Beads, 200 nm
Catalog Number	MGB-IP-004
Size	1 mL, 5 mL
Physical Specs	200 nm
Description	Protein L Magnetic Beads are composed of 200 nm magnetic nanoparticles covalently attached to Protein L. The nanometer-sized beads provide an exceptionally large specific surface area, resulting in higher binding density, lower dosage requirements, and reduced non-specific interactions. Recombinant Protein L, a 36 kDa protein isolated from Peptostreptococcus magnus, specifically binds to the kappa light chain of immunoglobulins without interfering with antigen recognition. Unlike Protein A and Protein G, which target the antibody Fc region, Protein L binds via light-chain interactions. It recognizes a broader spectrum of antibody classes, including IgG, IgM, IgA, IgE, and IgD, as well as scFv and Fab fragments. Protein L binds antibodies from human, mouse, rat, rabbit, and chicken sources but does not react with immunoglobulins from bovine, goat, or sheep species.
Applications	For immunoprecipitation (IP) or co-immunoprecipitation (Co-IP) of antigens in samples such as cell lysates, cell culture supernatants, serum, and ascites.
Particle Size	200 nm
Concentration	10 mg/mL
Ligand-binding Capacity	≥ 0.5 mg hlgG/mL beads
Storage	2-8°C

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