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| Product Name | Nexturastat A LNP,Nexturastat A liposome |
| Catalog Number | R-ZZTBSSDL-108 |
| Alias | HDAC6 selective inhibitor nanoformulation |
| Appearance | Milky white to off-white homogeneous suspension |
| Molecular Formula | N/A |
| Solubility | Can be reconstituted in physiological buffer or 5% glucose solution to form a stable colloidal dispersion system |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 year |
| Shipping Condition | low temperature transport |
| Application | Development of nano-delivery systems for poorly soluble HDAC inhibitors |
| Specification | 10mg:Inquiry 20mg:Inquiry 50mg:Inquiry |
| Description | Nexturastat A LNP is a specialized nanoliposome formulation of Nexturastat A, a selective histone deacetylase 6 (HDAC6) inhibitor. Nexturastat A inhibits HDAC6 activity with high selectivity, regulates the acetylation status of α-tubulin and other non-histone substrates, affects cytoskeletal stability, protein degradation and signal transduction, and displays anti-proliferation and pro-apoptosis activities in a variety of tumors and ST in vivo. However, its poor water solubility, rapid metabolism in vivo, and lack of targeting limit its clinical application potential. |