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Product Infomation
Product Name Nexturastat A LNP,Nexturastat A liposome
Catalog Number R-ZZTBSSDL-108
Alias HDAC6 selective inhibitor nanoformulation
Appearance Milky white to off-white homogeneous suspension
Molecular Formula N/A
Solubility Can be reconstituted in physiological buffer or 5% glucose solution to form a stable colloidal dispersion system
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Development of nano-delivery systems for poorly soluble HDAC inhibitors
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description Nexturastat A LNP is a specialized nanoliposome formulation of Nexturastat A, a selective histone deacetylase 6 (HDAC6) inhibitor. Nexturastat A inhibits HDAC6 activity with high selectivity, regulates the acetylation status of α-tubulin and other non-histone substrates, affects cytoskeletal stability, protein degradation and signal transduction, and displays anti-proliferation and pro-apoptosis activities in a variety of tumors and ST in vivo. However, its poor water solubility, rapid metabolism in vivo, and lack of targeting limit its clinical application potential.
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