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Product Infomation
Product Name ML348 loaded lipid nanoparticle-mannose
Catalog Number LNP-059
Size 10 mg; 25 mg; 50 mg
Alias ML348@LNP-mannose
Appearance White or off-white powder or granules
Solubility Soluble in organic solvents
Description ML348@LNP-MAN is a complex system constructed by combining the selective and reversible lysophospholipase 1 (LYPLA1)inhibitor ML348 with lipid nanoparticle (LNP)technology and equipped with mannose (MAN)targeting ligand. ML348 itself can inhibit LYPLA1 with an IC50 value of 210nM, and can also act on acyl protein thioesterase 1 (APT1), showing potential in related research such as huntington's condition. LNP has a lipid bilayer structure, which can effectively wrap ML348, protect it from premature degradation, and help the drug cross the biological membrane barrier with its good biocompatibility.
Applications Drug delivery
Storage -20°C, protected from light
Purity 95%+
Shelf Life 1 Year
Shipping Condition Low temperature transport
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