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Product Infomation
Product Name MAN-LNP@matrine, mannose-modified lipid nanoparticles loaded with matrine
Catalog Number R-KSJ256
Alias Mannose-LNP@matrine
Appearance Dispersion
Molecular Formula N/A
Solubility Dispersed in water
Storage 2-8°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Preparation of liposomes
Specification 10mg：Inquiry
20mg：Inquiry
50mg：Inquiry
Description MAN-LNP@matrine is a new nanodrug delivery system that integrates targeting, sustained release and biocompatibility. Among them, lipid nanoparticles (LNP) are used as carriers, mainly composed of lipid components such as phospholipids and cholesterol. They have good biocompatibility and degradability. They can effectively encapsulate matrine, protect drug activity, and prolong the circulation time of drugs in the body. Mannose (MAN) is modified on the surface of lipid nanoparticles and can specifically bind to mannose receptors on the cell surface, giving the system active targeting capabilities, allowing it to accurately enrich cells containing mannose receptors, such as tumor cells, immune cells, etc. Matrine is an alkaloid extracted from the traditional Chinese medicine Sophora flavescens. It has various pharmacological activities such as anti-inflammatory, anti-tumor, and anti-virus. However, it has problems such as poor water solubility and low bioavailability. Through the MAN-LNP@matrine system, it not only solves the delivery problem of matrine, but also achieves controlled release of the drug by adjusting the composition and structure of the lipid nanoparticles, improving the drug effect and reducing side effects.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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