We can offer a discount on bulk orders. Please contact our sales team for further inquiry.
Product Infomation
Product Name LNP-pDNA, plasmid DNA encapsulated in cationic lipid nanoparticles
Catalog Number R-LNP-100-01
Alias Cationic LNP package plasmid and water-soluble Fe3O4
Appearance Light yellow or colorless powder
Molecular Formula N/A
Solubility Soluble in organic solvents
Storage -20°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application gene therapy
Specification 100mg：Inquiry
500mg：Inquiry
1g: Inquiry
Description Cationic lipid nanoparticles (LNP) can efficiently encapsulate negatively charged plasmids through electrostatic interaction. LNPs are typically composed of cationic lipids, neutral helper lipids, cholesterol, and pegylated lipids. During preparation, the aqueous phase containing the plasmid is rapidly mixed with the organic phase in which the lipid is dissolved. The cationic lipid is protonated and positively charged, and is electrostatically combined with the phosphate backbone of the plasmid. The lipid components self-assemble around the plasmid into a nanostructure through hydrophobic and van der Waals forces. It can effectively protect plasmids from nuclease degradation, and can also use endocytosis to improve the efficiency of plasmids entering cells. It has great application potential in fields such as gene treatment and vaccine research and development. Water-soluble Fe₃O₄ nanoparticles are magnetic iron oxide nanomaterials. Through special preparation processes such as co-precipitation, hydrothermal, ligand exchange or surface modification (such as the introduction of carboxyl groups, sulfonic acid groups, etc.), it can be stably dispersed in water and is not prone to aggregation and precipitation. It has superparamagnetic properties and is quickly magnetized under the action of an external magnetic field. The magnetism disappears after the magnetic field is removed, which facilitates rapid separation and resuspension. It has a small size and a large specific surface area. The surface can bind biomolecules and impart specific functions. It is widely used in biomedical fields, such as magnetic resonance imaging, targeted drug delivery, cell separation, etc.
Online Inquiry
For Research or Industrial Raw Materials, Not For Personal Medical Use!
Place the Order
FAQs
logo

Enter your email here to subscribe.

Copyright © MATEXCEL. All Rights Reserved.
0
Inquiry Basket