Lificiguat (YC-1)lipid nanoparticle formulation

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Product Infomation

Product Name	Lificiguat (YC-1)lipid nanoparticle formulation
Catalog Number	LNP-014
Size	10 mg; 20 mg; 50 mg
Alias	Lificiguat (YC-1)LNP; Soluble guanylate cyclase activator nanodelivery system
Appearance	Milky white to light blue homogeneous suspension
Solubility	It can be dispersed in physiological buffer (such as PBS)or 5% glucose solution to form a stable colloidal dispersion system
Description	Lificiguat (YC-1)LNP is a specialized nano-lipid nanoparticle formulation of the soluble guanylyl cyclase (sGC)activator lificiguat (YC-1), encapsulated using the optimized formula FNT8P.2. Lificiguat (YC-1), as a small molecule compound with a dual mechanism of action, can not only activate sGC to enhance the cGMP signaling pathway, but also inhibit hypoxia-inducible factor-1α (HIF-1α), which has important research value in condition and other fields. However, its poor water solubility, rapid metabolism in the body, and insufficient tissue targeting limit its full effect.
Applications	Development of nanoformulation of poorly soluble sGC activator/HIF-1α inhibitor
Storage	4°C, protected from light
Purity	95%+
Shelf Life	1 Year
Shipping Condition	Low temperature transport

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