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| Product Name | Lificiguat (YC-1) LNP,Lificiguat (YC-1) liposome formulation |
| Catalog Number | R-ZZTBSSDL-105 |
| Alias | Soluble guanylate cyclase activator nanodelivery system |
| Appearance | Milky white to light blue homogeneous suspension |
| Molecular Formula | N/A |
| Solubility | Can be reconstituted in physiological buffer (such as PBS) or 5% glucose solution to form a stable colloidal dispersion system |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 year |
| Shipping Condition | low temperature transport |
| Application | Development of nanoformulation of poorly soluble sGC activator/HIF-1α inhibitor |
| Specification | 10mg:Inquiry 20mg:Inquiry 50mg:Inquiry |
| Description | Lificiguat (YC-1) LNP is a specialized nanoliposome formulation of the soluble guanylyl cyclase (sGC) activator Lificiguat (YC-1), encapsulated using the optimized formula FNT8P.2. Lificiguat (YC-1), as a small molecule compound with a dual mechanism of action, can not only activate sGC to enhance the cGMP signaling pathway, but also inhibit hypoxia-inducible factor-1α (HIF-1α), which has important research value in disease and other fields. However, its poor water solubility, rapid metabolism in the body, and insufficient tissue targeting limit its full effect. |