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Product Infomation
Product Name Lificiguat (YC-1) LNP,Lificiguat (YC-1) liposome formulation
Catalog Number R-ZZTBSSDL-105
Alias Soluble guanylate cyclase activator nanodelivery system
Appearance Milky white to light blue homogeneous suspension
Molecular Formula N/A
Solubility Can be reconstituted in physiological buffer (such as PBS) or 5% glucose solution to form a stable colloidal dispersion system
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Development of nanoformulation of poorly soluble sGC activator/HIF-1α inhibitor
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description Lificiguat (YC-1) LNP is a specialized nanoliposome formulation of the soluble guanylyl cyclase (sGC) activator Lificiguat (YC-1), encapsulated using the optimized formula FNT8P.2. Lificiguat (YC-1), as a small molecule compound with a dual mechanism of action, can not only activate sGC to enhance the cGMP signaling pathway, but also inhibit hypoxia-inducible factor-1α (HIF-1α), which has important research value in disease and other fields. However, its poor water solubility, rapid metabolism in the body, and insufficient tissue targeting limit its full effect.
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