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Product Infomation
Product Name HSPC-DSPE-mPEG2000 lipid nanoparticle
Catalog Number LNP-030
Size 10 mg; 20 mg; 50 mg
Alias HSPC-DSPE-mPEG2000 LNP; HSPC-DSPE-mPEG2000 (95-5, mol-mol)lipid nanoparticles
Appearance Translucent to milky white homogeneous dispersion
Solubility It can form a uniform and stable colloidal solution in the aqueous phase
Description HSPC-DSPE-mPEG2000 (95-5, mol-mol)lipid nanoparticles are cholesterol-free, pure PEGylated lipid nanoparticle systems using a simplified binary formulation of HSPC-DSPE-mPEG2000 (95: 5). This system uses high phase transition temperature HSPC (tm≈52-55°C)as the only matrix phospholipid to form a highly ordered gel-state rigid membrane, and directly achieves surface PEGylation modification through covalent anchoring of 5 mol% DSPE-mPEG2000. The core of its design is to explore the PEGylation effect and drug loading characteristics of pure gel phospholipid membranes under cholesterol-free conditions.
Applications Model system for the interaction of highly rigid membranes with PEG
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 Year
Shipping Condition Low temperature transport
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