HSPC-cholesterol-DSPE-mPEG2000-maleimide-MPL lipid nanoparticles

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Product Infomation

Product Name	HSPC-cholesterol-DSPE-mPEG2000-maleimide-MPL lipid nanoparticles
Catalog Number	LNP-022
Size	10 mg; 20 mg; 50 mg
Alias	HSPC-cholesterol-DSPE-mPEG2000-mal-MPL LNP; HSPC-chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49-45-4-1-1, mol-mol)lipid nanoparticles
Appearance	Milky white to slightly opalescent uniform dispersion system
Solubility	Forms stable and uniform colloidal dispersion system in aqueous buffer
Description	HSPC-chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49-45-4-1-1, mol-mol)lipid nanoparticles are highly functionalized complex immunomodulatory long-circulating lipid nanoparticles, using HSPC-chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49: 45: 4: 1: 1)five-element compound formula. This system uses highly stable HSPC-chol (49: 45)as the membrane base to ensure the structural integrity of the carrier and drug sustained release capability It provides long-circulation "stealth" properties by introducing 4 mol% DSPE-mPEG2000 It also integrates 1 mol% DSPE-mPEG2000-maleimide for site-specific coupling of ligands (such as antibodies, peptides), and 1 mol% monophosphoryl lipid A (MPL)as a TLR4 agonist immune adjuvant.
Applications	Development of targeting-immunomodulation dual-functional delivery system
Storage	4°C, protected from light
Purity	95%+
Shelf Life	1 Year
Shipping Condition	Low temperature transport

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