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Product Infomation
Product Name HSPC-Cholesterol-DSPE-mPEG2000-Mal-MPL LNP,HSPC-Cholesterol-DSPE-mPEG2000-maleimide-MPL liposomes
Catalog Number R-ZZTBSSDL-12
Alias HSPC-Chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49-45-4-1-1, mol-mol) Liposomes
Appearance Milky white to slightly opalescent uniform dispersion system
Molecular Formula N/A
Solubility Forms stable and uniform colloidal dispersion system in aqueous buffer
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Development of targeting-immunomodulation dual-functional delivery system
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description HSPC-Chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49-45-4-1-1, mol-mol) Liposomes are highly functionalized complex immunomodulatory long-circulating liposomes, using HSPC-Chol-DSPE-mPEG2000-DSPE-mPEG2000-maleimide-MPL (49:45:4:1:1) Five-element compound formula. This system uses highly stable HSPC-Chol (49:45) as the membrane base to ensure the structural integrity of the carrier and drug sustained release capability; it provides long-circulation "stealth" properties by introducing 4 mol% DSPE-mPEG2000; it also integrates 1 mol% DSPE-mPEG2000-maleimide for site-specific coupling of ligands (such as antibodies, peptides), and 1 mol% monophosphoryl lipid A (MPL) as a TLR4 agonist immune adjuvant.
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