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| Product Name | HSPC-cholesterol-DSPE-mPEG2000 lipid nanoparticles |
| Catalog Number | LNP-033 |
| Size | 10 mg; 20 mg; 50 mg |
| Alias | HSPC-cholesterol-DSPE-mPEG2000 LNP; Long-circulating PEGylated lipid nanoparticles |
| Appearance | Milky white to light yellow suspension |
| Solubility | Water (forms colloidal dispersion) |
| Description | HSPC-chol-DSPE-mPEG2000 lipid nanoparticles is a long-circulation, PEGylated lipid nanoparticle nanocarrier system prepared from three lipid components: hydrogenated soybean phosphatidylcholine (HSPC), cholesterol (chol)and distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-mPEG2000)through film hydration, extrusion and other processes. As the main phospholipid component, HSPC provides a stable bilayer structure and has a high phase transition temperature due to its saturated fatty acid chain, which enhances the stability of lipid nanoparticles during storage and circulation. Cholesterol is used to regulate membrane fluidity, improve stability and reduce drug leakage. |
| Applications | Nucleic acid (siRNA, mRNA)lipid nanoparticle carrier |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 Year |
| Shipping Condition | Low temperature transport |