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Product Infomation
Product Name HSPC-cholesterol-DSPE-mPEG2000 lipid nanoparticles
Catalog Number LNP-033
Size 10 mg; 20 mg; 50 mg
Alias HSPC-cholesterol-DSPE-mPEG2000 LNP; Long-circulating PEGylated lipid nanoparticles
Appearance Milky white to light yellow suspension
Solubility Water (forms colloidal dispersion)
Description HSPC-chol-DSPE-mPEG2000 lipid nanoparticles is a long-circulation, PEGylated lipid nanoparticle nanocarrier system prepared from three lipid components: hydrogenated soybean phosphatidylcholine (HSPC), cholesterol (chol)and distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-mPEG2000)through film hydration, extrusion and other processes. As the main phospholipid component, HSPC provides a stable bilayer structure and has a high phase transition temperature due to its saturated fatty acid chain, which enhances the stability of lipid nanoparticles during storage and circulation. Cholesterol is used to regulate membrane fluidity, improve stability and reduce drug leakage.
Applications Nucleic acid (siRNA, mRNA)lipid nanoparticle carrier
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 Year
Shipping Condition Low temperature transport
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