HSPC-CHOL LNP with (NH₄)₂SO₄ Gradient

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Product Infomation

Product Name	HSPC-CHOL LNP with (NH₄)₂SO₄ Gradient
Catalog Number	R-ZZTBSSDL-125
Alias	Hydrogenated soybean phosphatidylcholine-cholesterol liposomes with ammonium sulfate gradient (molar ratio 55:45, particle size 100nm),
Appearance	Milky white homogeneous suspension
Molecular Formula	N/A
Solubility	Can be reconstituted/diluted in isotonic buffer (such as HEPES buffered saline, PBS) to form a stable colloidal dispersion system
Storage	4°C, protected from light
Purity	95%+
Shelf Life	1 year
Shipping Condition	low temperature transport
Application	Preformulation studies of long-circulating nanomedicines
Specification	10mg：Inquiry 20mg：Inquiry 50mg：Inquiry
Description	HSPC-CHOL LNP with (NH₄)₂SO₄ Gradient is a blank liposome platform specially designed for active drug loading (Remote Loading). It is constructed with a stable membrane formula HSPC:CHOL (55:45 mol:mol), and the particle size is accurately controlled at ~100 nm through extrusion technology. Its core feature is that a high-concentration ammonium sulfate solution environment (usually 250 mM or higher) is established in the inner aqueous phase of the liposome, while the outer aqueous phase is an isotonic ammonium-free buffer, thereby forming an ammonium sulfate chemical gradient (a type of pH gradient) across the lipid bilayer.

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