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Product Infomation
Product Name High-throughput Membrane-based Microfluidic Chip
Catalog Number OOC-007
Description The high-throughput membrane barrier chip is a versatile, high-throughput membrane-based chip with independent upper and lower flow channels. These channels are separated by a biocompatible porous membrane, allowing cells in the upper and lower layers to interact through the membrane and construct a tissue-tissue barrier interface structure similar to that found in the human body. Gravity-driven fluid flow within the chip ensures sustainable circulation, facilitating sufficient exchange of oxygen and nutrients.
Applications Construction of barrier organoid models, such as lung, liver, intestine, skin, kidney, heart, blood-brain barrier, and immune co-culture models; basic scientific research, such as cell interactions, inflammatory mechanisms, tumor migration, and gut microbiota; high-throughput drug screening and toxicity assessment; cosmetic safety and efficacy evaluation; construction of disease models, such as IPF and IBD models.
Features It reliably enables the construction of classic multi-layer and barrier-function organ-on-a-chip models. The upper and lower chambers are independently controlled, allowing for continuous perfusion culture via gas-liquid or liquid-liquid methods. Separated by a porous membrane, the chambers simulate the hierarchical structure of tissue interfaces in human organs, enabling the exchange of substances and signals. Operation is simple and does not require complex fluid control systems, reducing experimental complexity. When used with a rocking perfusion device, continuous dynamic culture is achieved, ensuring thorough nutrient exchange. It offers high throughput and low cost per model.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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