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Product Infomation
Product Name High-throughput Droplet Chip (Step Emulsification Chip)
Catalog Number MC-SPC-032
Physical Specs PDMS chip: 62*19*2 mm; B270 glass: 75*25*2 mm
Description A step emulsion droplet chip typically consists of a continuous-phase channel, a dispersed-phase channel, a step structure (also known as a step-down structure), and a droplet output channel. Among these, the step structure is the key region for droplet generation. It is typically a suddenly expanding chamber or an array of micropores that triggers droplet breakage through a sudden change in geometry; that is, the principle of droplet generation is the sudden drop in Laplace pressure as the dispersed phase passes over the step. The size of the droplets depends on the device geometry and is insensitive to fluctuations in the flow rate of the input dispersed phase. In the step emulsification process, nozzle depth is the primary parameter affecting droplet size, while platform length has a minor influence. Droplet diameter is linearly related to nozzle height.
Applications Preparation of drug-loaded microspheres to achieve sustained-release or targeted delivery, improving therapeutic efficacy and reducing side effects; encapsulation of proteins, peptides, and nucleic acids to protect their biological activity and control release kinetics; enteric-coated microspheres for acid-sensitive drugs to enhance stability; encapsulation of stem cells or progenitor cells to provide a 3D growth microenvironment; sustained release of factors such as VEGF and BMP-2 to promote angiogenesis or bone repair; Biodegradable microspheres serve as temporary scaffolds to aid tissue regeneration; protect vitamins, probiotics, and other substances from the effects of processing or the digestive environment; release flavor compounds under specific conditions; encapsulate retinol, vitamin C, and other substances to reduce irritation and prolong efficacy; uniformly disperse physical sunscreen agents such as titanium dioxide to improve skin feel; Immobilizing microorganisms or enzymes; encapsulating materials such as paraffin for building energy conservation or temperature control in electronic devices; extending the duration of action of pesticides/herbicides to reduce application frequency; improving the stability of antibiotics or vaccines; encoding microspheres for multiplex detection; using magnetic microspheres to separate target molecules; microspheres of uniform size to improve separation efficiency; serving as functional fillers in photopolymerizable resins.
Material PDMS & B270 Glass
Manufacturing Process Soft lithography, plasma-assisted bonding
Pressure Resistance 2500 mbar
Flow Channel Surface Modification Hydrophobic
Supporting Fixtures Microfluidic chip fixture
Droplet Diameter 50-65 μm, 50-100 μm
Flow Rate 10-1000 μL/min (CV<5%)
Accessories Microfluidic chip holder; microdroplet generation oil (available in 2% and 5% concentrations)
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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