Gilteritinib lipid nanoparticle

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Product Infomation

Product Name	Gilteritinib lipid nanoparticle
Catalog Number	LNP-017
Size	10 mg; 20 mg; 50 mg
Alias	Gilteritinib (ASP2215)LNP; ASP2215 long-circulating targeted lipid nanoparticles
Appearance	Off-white to light yellow homogeneous opalescent suspension
Solubility	It can be dispersed in physiological buffer (such as PBS)or 5% glucose solution to form a stable colloidal system
Description	Gilteritinib (ASP2215)lipid nanoparticles are specialized nano-lipid nanoparticle formulations targeting the dual inhibitor of FLT3/AXL kinase, gilteritinib/ASP2215. This formulation uses an optimized long-circulating lipid nanoparticle formulation and is designed to solve the problems of gilteritinib's limited water solubility, unstable oral bioavailability, and insufficient targeting in the ST or bone marrow microenvironment. Through nano-encapsulation technology, gitertinib is encapsulated in the lipid bilayer or internal aqueous phase to improve its apparent solubility and in vitro stability.
Applications	Nanoformulation formulation development of poorly soluble kinase inhibitors
Storage	4°C, protected from light
Purity	95%+
Shelf Life	1 Year
Shipping Condition	Low temperature transport

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