Gilteritinib (ASP2215) LNP, Gilteritinib liposome

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Product Infomation

Product Name	Gilteritinib (ASP2215) LNP, Gilteritinib liposome
Catalog Number	R-ZZTBSSDL-102
Alias	ASP2215 long-circulating targeted liposomes
Appearance	Off-white to light yellow homogeneous opalescent suspension
Molecular Formula	N/A
Solubility	Can be dispersed in physiological buffer (such as PBS) or 5% glucose solution to form a stable colloidal system
Storage	4°C, protected from light
Purity	95%+
Shelf Life	1 year
Shipping Condition	low temperature transport
Application	Nanoformulation formulation development of poorly soluble kinase inhibitors
Specification	10mg：Inquiry 20mg：Inquiry 50mg：Inquiry
Description	Gilteritinib (ASP2215) Liposomes are specialized nanoliposome formulations targeting the dual inhibitor of FLT3/AXL kinase, Gilteritinib/ASP2215. This formulation uses an optimized long-circulating liposome formulation and is designed to solve the problems of gilteritinib's limited water solubility, unstable oral bioavailability, and insufficient targeting in the ST or bone marrow microenvironment. Through nano-encapsulation technology, gitertinib is encapsulated in the lipid bilayer or internal aqueous phase to improve its apparent solubility and in vivo stability.

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