We can offer a discount on bulk orders. Please contact our sales team for further inquiry.
Product Infomation
Product Name DSPE-HYD-PEGLNP@DEX, distearoylphosphatidylethanolamine-hydrazone bond-polyethylene glycol lipid nanoparticles encapsulating dexamethasone
Catalog Number R-CW-DP001-2k
Alias Responsive phospholipid-encapsulated drugs
Appearance Dispersion​
Molecular Formula N/A
Solubility Stable dispersion in aqueous media such as water and physiological saline
Storage 2-8°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application drug delivery system
Specification 10mg：Inquiry
20mg：Inquiry
50mg：Inquiry
Description DSPE-HYD-PEGLNP@DEX is a liposome drug delivery system that integrates targeting, responsiveness and drug sustained release functions. It uses distearoylphosphatidylethanolamine (DSPE) and polyethylene glycol (PEG) as the main lipid materials, connected through hydrazone bonds (-C=N-NH-) to form amphipathic lipid molecules, which can self-assemble to form lipid nanoparticles and encapsulate dexamethasone in them. DSPE has good film-forming properties and biofilm compatibility, and can form the hydrophobic core of lipid nanoparticles; PEG gives the nanoparticles good water solubility and steric hindrance effect, reducing recognition and clearance by the immunity system, and prolonging the time in the body circulation; the hydrazone bond is sensitive to acidic environments, and will be rapidly hydrolyzed and broken in acidic microenvironments (pH 5.0-6.5) such as tumor tissue, prompting the release of dexamethasone. Dexamethasone has a variety of activities. After being encapsulated by the lipid nanoparticles, targeted delivery and controlled release of the drug can be achieved, improving the drug effect and reducing systemic side effects.
Online Inquiry
For Research or Industrial Raw Materials, Not For Personal Medical Use!
Place the Order
FAQs
logo

Enter your email here to subscribe.

Copyright © MATEXCEL. All Rights Reserved.
0
Inquiry Basket