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Product Infomation
Product Name DPPC LNP@berberin, dipalmitoylphosphatidylcholine lipid nanoparticles loaded with berberine
Catalog Number R-DPPC-051
Alias DPPC liposome-encapsulated berberine
Appearance Dispersion
Molecular Formula N/A
Solubility Stable dispersion in aqueous solution
Storage 2-8°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application drug delivery system
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description DPPC LNP@berberin is a drug-loaded complex that combines the natural active ingredient berberine with dipalmitoylphosphatidylcholine lipid nanoparticles. Berberine, as an isoquinoline alkaloid extracted from Coptis chinensis and other Chinese medicinal materials, has various pharmacological activities such as Antibacterial. However, its application is limited due to its poor water solubility, low bioavailability, and rapid metabolism in the body. As an important component of biological membranes, DPPC has good biocompatibility and degradability. The lipid nanoparticles formed by its self-assembly can effectively encapsulate berberine, which not only improves the water solubility of berberine, but also protects the drug from rapid degradation by enzymes in the body and prolongs the circulation time of the drug in the body. By modifying the surface of lipid nanoparticles, targeted delivery to specific tissues or cells can also be achieved, further increasing the enrichment concentration of berberine in the target site, enhancing the treatment effect, and reducing side effects on normal tissues.
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