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Product Infomation
Product Name DOX-LNP-PEG, doxorubicin-loaded lipid nanoparticles-polyethylene glycol
Catalog Number R-Z-03-5k
Alias Doxorubicin-loaded lipid nanoparticles-polyethylene glycol complex
Appearance Dispersion
Molecular Formula N/A
Solubility Water, methanol, ethanol, dimethyl sulfoxide (DMSO)
Storage 2-8°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Targeted delivery of compounds
Specification 5ml: Inquiry
10ml: Inquiry
20ml: Inquiry
Description DOX-LNP-PEG is a drug delivery system. Doxorubicin is embedded in the DNA double strands of tumor cells, interferes with DNA replication and transcription, and exerts harmful effects on cells. As a carrier, lipid nanoparticles (LNP) have good biocompatibility and can effectively encapsulate doxorubicin, protect the drug from premature degradation or removal, and improve drug stability. At the same time, LNPs can adjust particle size and surface properties to facilitate drug transport and distribution in the body. Polyethylene glycol (PEG) is modified on the surface of LNP and has multiple effects. On the one hand, the hydrophilicity of PEG forms a hydration layer on the surface of LNP, reducing the adsorption of biological macromolecules such as proteins on its surface, reducing the probability of being recognized and cleared by the immunity system, thereby prolonging the circulation time of the complex in the body. On the other hand, PEG can reduce the interaction between nanoparticles, prevent nanoparticle aggregation, and enhance the stability of the system.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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