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Product Infomation
Product Name DOTAP LNP@RNA-VHPKOHRGGSKGC
Catalog Number R-VHGD-101
Alias Polypeptide (VHPKOHRGGSKGC) modified 1,2-dioleoyl-3-trimethylammonium propane liposome to encapsulate ribonucleic acid
Appearance Dispersion
Molecular Formula N/A
Solubility Chloroform, methanol, PBS buffer
Storage -20°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Targeted delivery of compounds
Specification 10ml: Inquiry
20ml: Inquiry
50ml: Inquiry
Description Polypeptide (VHPKOHRGGSKGC) modified DOTAP liposomes encapsulate RNA. DOTAP (1,2-dioleoyl-3-trimethylammonium propane) liposomes are modified with a polypeptide (VHPKOHRGGSKGC) of a specific sequence to encapsulate RNA. The peptide (VHPKOHRGGSKGC) has special functions. VHPKQHRGGSKGC can specifically recognize and bind to Blood vessels cell adhesion molecule-1 (VCAM-1). The peptides in this product also have specific targeting or function enhancement effects. As a carrier, the positively charged nature of DOTAP liposomes helps to combine with negatively charged RNA through electrostatic interaction to achieve efficient encapsulation. The liposome structure can protect RNA from degradation by external nucleases and extend its existence time in and outside the body. Modified liposomes can change their surface properties, such as enhancing targeting, prolonging circulation time, etc., improving the delivery efficiency of RNA, allowing it to reach the target site more accurately and exert its effect.
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For Research or Industrial Raw Materials, Not For Personal Medical Use!
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