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Product Infomation
Product Name DOTAP-DOPE lipid nanoparticle
Catalog Number LNP-006
Size 10 mg; 20 mg; 50 mg
Alias DOTAP-DOPE LNP; Standard vector for gene/nucleic acid delivery
Appearance Milky white to translucent homogeneous suspension
Solubility It can be dispersed in aqueous buffer to form a stable colloidal dispersion system
Description DOTAP-DOPE LNP is a cationic lipid nanoparticle system composed of cationic lipid DOTAP (positively charged)and auxiliary phospholipid DOPE (neutral)in an equal molar ratio (50: 50). DOTAP provides positive charges, effectively combines and compresses negatively charged nucleic acids (such as DNA, siRNA, and mRNA)through electrostatic interaction to form a stable lipid/nucleic acid complex DOPE acts as a "fusion lipid" to promote the fusion of lipid nanoparticles and cell membranes and endosomal escape, improving the intracellular delivery efficiency of nucleic acids.
Applications In vitro cell gene transfection and protein expression research
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 Year
Shipping Condition Low temperature transport
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