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| Product Name | DOTAP-DOPE lipid nanoparticle |
| Catalog Number | LNP-006 |
| Size | 10 mg; 20 mg; 50 mg |
| Alias | DOTAP-DOPE LNP; Standard vector for gene/nucleic acid delivery |
| Appearance | Milky white to translucent homogeneous suspension |
| Solubility | It can be dispersed in aqueous buffer to form a stable colloidal dispersion system |
| Description | DOTAP-DOPE LNP is a cationic lipid nanoparticle system composed of cationic lipid DOTAP (positively charged)and auxiliary phospholipid DOPE (neutral)in an equal molar ratio (50: 50). DOTAP provides positive charges, effectively combines and compresses negatively charged nucleic acids (such as DNA, siRNA, and mRNA)through electrostatic interaction to form a stable lipid/nucleic acid complex DOPE acts as a "fusion lipid" to promote the fusion of lipid nanoparticles and cell membranes and endosomal escape, improving the intracellular delivery efficiency of nucleic acids. |
| Applications | In vitro cell gene transfection and protein expression research |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 Year |
| Shipping Condition | Low temperature transport |