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Product Infomation
Product Name DMTAP-DOPE Cationic LNP, dimyristoyltrimethylammonium propane-dioleoylphosphatidylethanolamine cationic liposomes
Catalog Number R-ZZTBSSDL-131
Alias Temperature-sensitive cationic liposomes
Appearance Milky white to translucent homogeneous suspension
Molecular Formula N/A
Solubility Can be reconstituted in nuclease-free water or HEPES buffer to form a stable colloidal dispersion.
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Gene function studies requiring long-term cell culture and observation
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description DMTAP-DOPE Cationic LNP is a medium phase transition temperature cationic liposome system based on the medium-chain saturated cationic lipid DMTAP. It is compounded of the cationic lipid DMTAP (dimyristoyltrimethylammonium propane, phase transition temperature ~23°C) and the neutral auxiliary phospholipid DOPE in a specific ratio. DMTAP has high membrane fluidity at physiological temperatures, and its shorter saturated carbon chain (C14) can reduce cellular Tox compared to long-chain cationic lipids (such as DOTAP) while maintaining nucleic acid binding ability; DOPE promotes the fusion of liposomes and endosomal membranes with its conical molecular structure, effectively mediating endosomal escape.
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