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Product Infomation
Product Name DIO and paclitaxel encapsulated in lipid nanoparticles
Catalog Number LNP-071
Size 10 mg; 20 mg; 50 mg
Alias LNP@DIO-PTX; Lipid nanoparticles encapsulating 1, 1'-dioctyl-3, 3, 3', 3'-tetramethylindocyanine perchlorate-paclitaxel
Appearance Dispersion
Solubility Dispersed in water or PBS buffer
Description LNP@DIO-PTX is a constructed nanocomplex that encapsulates 1, 1′-dioctyl-3, 3, 3′, 3′-tetramethylindocyanine perchlorate-labeled paclitaxel inside lipid nanoparticles. Lipid nanoparticles are mainly composed of ionizable cationic phospholipids, cholesterol, auxiliary phospholipids and polyethylene glycol modified phospholipids. Under physiological pH conditions, ionizable cationic phospholipids are neutral, protonated and positively charged in acidic environments such as endosomes, and can be closely combined with negatively charged or polar DIO-PTX through electrostatic interactions, hydrophobic interactions, etc.
Applications Preparation of lipid nanoparticles
Storage 2-8°C, protected from light
Purity 95%+
Shelf Life 1 Year
Shipping Condition Low temperature transport
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