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| Product Name | DIO and paclitaxel encapsulated in lipid nanoparticles |
| Catalog Number | LNP-071 |
| Size | 10 mg; 20 mg; 50 mg |
| Alias | LNP@DIO-PTX; Lipid nanoparticles encapsulating 1, 1'-dioctyl-3, 3, 3', 3'-tetramethylindocyanine perchlorate-paclitaxel |
| Appearance | Dispersion |
| Solubility | Dispersed in water or PBS buffer |
| Description | LNP@DIO-PTX is a constructed nanocomplex that encapsulates 1, 1′-dioctyl-3, 3, 3′, 3′-tetramethylindocyanine perchlorate-labeled paclitaxel inside lipid nanoparticles. Lipid nanoparticles are mainly composed of ionizable cationic phospholipids, cholesterol, auxiliary phospholipids and polyethylene glycol modified phospholipids. Under physiological pH conditions, ionizable cationic phospholipids are neutral, protonated and positively charged in acidic environments such as endosomes, and can be closely combined with negatively charged or polar DIO-PTX through electrostatic interactions, hydrophobic interactions, etc. |
| Applications | Preparation of lipid nanoparticles |
| Storage | 2-8°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 Year |
| Shipping Condition | Low temperature transport |