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Product Infomation
Product Name Colon-on-a-Chip
Catalog Number OOC-035
Description Mechanical forces applied to the colonic organ-on-a-chip provide experimental conditions that more closely resemble the in vivo environment. Under dynamic conditions, cells differentiate into specific cell populations and structures, forming the intestinal barrier and microvilli. This stands in stark contrast to traditional cell culture, which features limited cell populations with low differentiation levels and lacks physical stimulation.
Applications Used to investigate the mechanisms of colitis and immune cell recruitment to identify novel anti-inflammatory drug candidates.
Features Advanced human-derived cell models; physiologically relevant morphology; inclusion of multiple epithelial cell types; in vivo-like transcriptomic profiles; relevant barrier function.
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