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Product Infomation
Product Name Clophosome-A (Anionic) Control LNP, Clophosome-A (Anionic) Control LNP
Catalog Number R-ZZTBSSDL-121
Alias Phosphate buffer liposome control
Appearance Milky white homogeneous suspension
Molecular Formula N/A
Solubility Can be reconstituted in physiological buffer or sterile PBS to form a stable colloidal dispersion system
Storage 4°C, protected from light
Purity 95%+
Shelf Life 1 year
Shipping Condition low temperature transport
Application Controlled experiments to distinguish drug effects from vehicle effects
Specification 10mg:Inquiry
20mg:Inquiry
50mg:Inquiry
Description Clophosome-A (Anionic) Control Liposomes are special negative controls for clodronate liposome (Clophosome) experiments. They use exactly the same lipid composition, preparation process and physical and chemical properties (including particle size, surface charge and concentration) as active Clophosome products. The only difference is that the internal aqueous phase does not contain clodronate active drug and is filled with isotonic phosphate buffer saline (PBS). This design ensures that the control liposomes have exactly the same biodistribution, cellular uptake, and metabolic behavior as the active formulation in both in vitro and in vivo experiments, allowing accurate differentiation of macrophage-depleting effects of clodronate itself from nonspecific effects that may be caused by the liposomal vehicle.
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