We can offer a discount on bulk orders. Please contact our sales team for further inquiry.
Product Infomation
Product Name Chips for Constructing Vascular Models
Catalog Number OOC-001
Physical Specs 75*25*7 mm
Description This chip is an ideal microfluidic platform for constructing vascular models. For example, endothelial cells lining the inner walls of arterial vessels are directly exposed to blood flow, which exerts a tangential force (shear stress) on the endothelial surface. By applying a preset shear stress via a pneumatic perfusion system, cells can modulate various biological responses through mechanotransduction processes in response to mechanical stimulation. The chip design features two independent channels. The inlet and outlet reservoirs of each channel are connected to the pneumatic perfusion system via tower connectors, allowing cells to be seeded directly onto the bottom of the flow channels (cells with poor adhesion can be seeded after coating treatment, such as with extracellular matrix or poly-L-lysine). It can reconstruct dynamic microenvironments under different (physiological and pathological) flow rate conditions, and is applicable to studies of interactions between cells and perfused immune cells, circulating tumor cells (CTCs), or bacteria in monolayer, and double-layer cultures, as well as studies on interactions between cells and perfused immune cells, circulating tumor cells (CTCs), or bacteria.
Applications Used for cell culture under flow conditions. Includes: seeding a monolayer of cells on the channel surface; seeding monolayers of cells on both the bottom and top surfaces of the channel to study interactions between cultured cells and perfused immune cells, circulating tumor cells (CTCs), or bacteria; and seeding a bilayer of cells on the channel surface
Features Compatible with any type of inverted optical microscope (brightfield, fluorescence, confocal, etc.); the combination of glass and PDMS offers excellent biocompatibility and is non-toxic; PDMS provides good light transmission and high permeability to gases (such as oxygen and carbon dioxide), facilitating gas exchange and maintaining a 5% carbon dioxide environment within the chip; facilitates the recovery of cell cultures from the chip for subsequent experiments; low cost.
Material PDMS & B270 Glass
Depth 375 μm (channel)
Width 1.5 mm (channel)
Length 42.5 mm (channel)
Volume 24 μL (total fill volume)
Accessories Comes standard with 4 L-shaped barbed connectors (1.6 mm) and a 1-meter silicone tube (outer diameter 3 mm, inner diameter 1 mm)
Online Inquiry
For Research or Industrial Raw Materials, Not For Personal Medical Use!
Place the Order
FAQs
logo

Enter your email here to subscribe.

Copyright © MATEXCEL. All Rights Reserved.
0
Inquiry Basket