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| Product Name | Bionic Barrier-on-a-Chip |
| Catalog Number | OOC-023 |
| Description | The chip is fabricated using biocompatible materials via microfabrication technology. It comprises two independent cell culture chambers-upper and lower-connected by a semi-transparent porous membrane that facilitates communication and interaction between the cells in both layers. This design enables the co-culture of two or more cell types while supporting microfluidic perfusion. This system mimics human blood flow, continuously supplying nutrients to the tissue cells and removing metabolic byproducts. |
| Applications | Used to simulate the 3D physiological and pathological microenvironments at various tissue-tissue interfaces in the human body. This primarily includes the blood-brain barrier, the lung-blood barrier, the placental barrier, the glomerular filtration barrier, the intestinal-vascular barrier, and the tumor-vascular barrier. It is also used to simulate physiological and pathological processes such as cell invasion within the matrix and the vascularization of three-dimensional tissues and organs. |