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| Product Name | A939572 lipid nanoparticle |
| Catalog Number | LNP-012 |
| Size | 10 mg; 20 mg; 50 mg |
| Alias | A939572 LNP; Stearoyl-CoA desaturase 1 inhibitor nanoformulation |
| Appearance | Milky white to light yellow homogeneous suspension |
| Solubility | It can be dispersed in physiological buffer (such as PBS)or 5% glucose solution to form a stable colloidal system |
| Description | A939572 LNP is a specialized nano-lipid nanoparticle formulation targeting the inhibitor A939572 of stearoyl-CoA desaturase 1 (SCD1). A939572 inhibits SCD1 activity and interferes with the synthesis of monounsaturated fatty acids (such as oleic acid), thereby affecting cell membrane integrity, signal transduction and energy metabolism, and shows anti-proliferative activity in a variety of tumors (especially metabolism-dependent tumors). However, its poor water solubility, insufficient in vitro stability and lack of tissue targeting limit its full effect. |
| Applications | Study on the pharmacodynamics and mechanism of SCD1 inhibitors in vitro |
| Storage | 4°C, protected from light |
| Purity | 95%+ |
| Shelf Life | 1 Year |
| Shipping Condition | Low temperature transport |