Polyether F127 Diacrylate
Catalog No: HPB-018
Size: 1g/bottle, includes 0.05g of initiator LAP
5g/bottle, includes 0.25g of initiator LAP
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| Application | Injectable drug delivery,cell encapsulation,biomedical coatings |
| Introduction | Polyether F127 (also known as poloxamer) is a synthetic A-B-A type triblock copolymer with a molecular structure of polyethylene glycol-polypropylene glycol-polyethylene glycol. The polypropylene glycol segment in the middle of the F127 molecule is relatively hydrophobic, while the polyethylene glycol segments at both ends are relatively hydrophilic. This hydrophilic and hydrophobic property enables it to self-assemble into nano-micelles in water, and is often used for solubilization and loading of hydrophobic drugs. In addition, F127 has the property of thermo-gelling upon heating, that is, the F127 solution is a fluid at low temperatures, and when the temperature is increased, the solution solidifies into a reversible physical gel. The above special physical and chemical properties enable F127 to be used as a drug carrier, wound dressing, surfactant, 3D printing ink preparation, etc. Polyether F127 Diacrylate (F127DA) is endowed with photocuring ability by introducing propylene groups into the F127 molecular chain. F127DA photocurable hydrogel self-assembles into nano-micelles in water. Its core is a hydrophobic segment and its shell is a hydrophilic segment. It can be evenly dispersed in water as a cross-linker and active drug carrier to enhance the dispersibility of hydrophobic substances. In addition, the hydrogel also has excellent thermo-induced gelation (heating gelation) properties, good biosafety, and high strength and high toughness mechanical properties. The products launched by our team have passed strict raw material screening and quality testing, and have stable physical and chemical properties. They solidify into gel within 10 seconds under visible light irradiation. The material has strong scalability and can provide a variety of viscoelastic properties to adapt to the biomedical field, such as drug carriers, wound dressings, cell carrier shear protectants, biological 3D printing, etc. |
| Description | This material set includes polyether F127 diacrylate and photoinitiator LAP. |
| Application Areas | Preparation of high-strength hydrogels, drug carriers, biological 3D printing, tissue engineering, etc. |
| Appearance | White sponge-like |
| Mw | ~15 kDa |
| Storage | Dry package: room temperature, 3 months; 4℃, 12 months; -20℃, 18 months. |
| Package Size | 1g/bottle, includes 0.05g of initiator LAP 5g/bottle, includes 0.25g of initiator LAP |
| Degree of Substitution | ≥ 90% |
! For Research/Industry Use Only!